This paper aims to present a design of a web-user interface for mathematical model of glucose-insulin system. Nurses and administrative personnel can confirm the measured parameters entered by Lab technician. These parameters include glucose and insulin concentration in the heart, the liver and tissues. Measured and estimated parameters are stored in the database, the system displays the results evaluated and calculated by the system to serve as a point of reference to allow users making appropriate, and timely decisions. The front end is designed to be user friendly and to ease the user’s manipulation and the back end which is the hidden part embodies the database that stores measured and estimated parameters as well as the mathematical model which is programmed to calculate automatically the parameters and displays the results finally.