Histopathologic tests improve with sub-atomic measures since they increment particularity and, sometimes, responsiveness. wh--n microorganisms are undetected by histochemical approaches, are present in low amounts, stain ineffectively, are uncultivable, or have an surprising morphology, sub-atomic techniques for recognizable proof might be very advantageous. Atomic methodologies are valuable for the fast, explicit, and quantitative distinguishing proof of microorganisms in different circumstances