Neuroanatomy, the study of the structure and organization of the nervous system, reveals an intricate web of connections that underlie the complexity of the human brain. While there is a remarkable degree of consistency in the basic neuroanatomical organization across individuals, there exist unique features in certain regions of the brain that contribute to specialized functions and behaviors. This mini-review aims to explore some of these distinctive neuroanatomical features, focusing on the hippocampus, cerebellum, and corpus callosum. We discuss their structural characteristics, functional significance, and implications for cognition and behavior. By understanding these unique neuroanatomical aspects, we gain insights into the remarkable diversity of the human brain.