Gastro Intestinal Stromal Tumors (GIST) are submucosal tumors originating from the interstitial cells of canal located within the muscle layer from the digestive tract especially the stomach, small intestine, mesentery, colon and esophagus. GISTS are most common in the stomach (50%-70%), small intestine (20%-30%) and large intestine (about 10%). More rarely, it can be localized in other areas, such as the omentum and mesentery. Typically, more than 90% have a specific KIT or PDGFRA gene mutation. In this case report, we aimed to investigate the diagnosis and treatment of gastrointestinal stromal tumor of the small intestine detected in a patient who presented with partial intestinal obstruction.