44 2033180199

Wnt inhibition may limit human salivary gland cancer progression

Anita Joy*, Donald Reed, Aaron Altman, Kathryn Carter, Joshua Welborn

β-catenin is a multifunctional protein in the Wnt pathway, and acts as an intermediate for the association of the plasma membrane with the actin cytoskeleton, through binding E-cadherin and α-catenin. Its role as a linker protein between cells is crucial in maintaining E-cadherin’s adhesive properties. We aimed to evaluate β-catenin’s role in indirectly regulating cellcell adhesion and thereby influencing cell migration in an in vitro cell culture model


 
Publication d'évaluation par les pairs pour les associations, les sociétés et les universités pulsus-health-tech
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